Cumulative exposure to high remnant-cholesterol concentrations increases the risk of cardiovascular disease in patients with hypertension: a prospective cohort study

Autor: Weiqiang Wu, Guanzhi Chen, Kuangyi Wu, Huancong Zheng, Yanjuan Chen, Xianxuan Wang, Zegui Huang, Zefeng Cai, Zhiwei Cai, Zhichao Chen, Yulong Lan, Shuohua Chen, Shouling Wu, Youren Chen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-11 (2023)
Druh dokumentu: article
ISSN: 1475-2840
DOI: 10.1186/s12933-023-01984-4
Popis: Abstract Background The relationship of cumulative remnant-cholesterol (Cum-RC) concentration with the risk of cardiovascular disease (CVD) in patients with hypertension remains unclear. Methods We studied data for 28,698 individuals for whom three consecutive total cholesterol, high-density lipoprotein-cholesterol (HDL-C), and triglyceride concentrations were available, and who did not have CVD (14,349 with hypertension and 14,349 without), that was collected between 2006 and 2010. Participants with hypertension were placed into four groups based on Cum-RC quartile: a Q1 group (
Databáze: Directory of Open Access Journals
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