Genome Sequencing of a Camelpox Vaccine Reveals Close Similarity to Modified Vaccinia virus Ankara (MVA)

Autor: Maurilia Marcacci, Abdelmalik I. Khalafalla, Zulaikha M. Al Hammadi, Federica Monaco, Cesare Cammà, Mohammed F. Yusof, Saeed M. Al Yammahi, Iolanda Mangone, Fabrizia Valleriani, Mohamed A. Alhosani, Nicola Decaro, Alessio Lorusso, Salama S. Almuhairi, Giovanni Savini
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Viruses, Vol 12, Iss 8, p 786 (2020)
Druh dokumentu: article
ISSN: 1999-4915
DOI: 10.3390/v12080786
Popis: Camelpox is a viral contagious disease of Old-World camelids sustained by Camelpox virus (CMLV). The disease is characterized by mild, local skin or severe systemic infections and may have a major economic impact due to significant losses in terms of morbidity and mortality, weight loss, and low milk yield. Prevention of camelpox is performed by vaccination. In this study, we investigated the composition of a CMLV-based, live-attenuated commercial vaccine using next-generation sequencing (NGS) technology. The results of this analysis revealed genomic sequences of Modified Vaccinia virus Ankara (MVA).
Databáze: Directory of Open Access Journals
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