MHC class IIa haplotypes derived by high-throughput SNP screening in an isolated sheep population

Autor: Kara L Dicks, Josephine M Pemberton, Keith T Ballingall, Susan E Johnston
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: G3: Genes, Genomes, Genetics, Vol 11, Iss 10 (2021)
Druh dokumentu: article
ISSN: 2160-1836
DOI: 10.1093/g3journal/jkab200
Popis: AbstractInvestigating the current evolutionary processes acting on a highly polymorphic gene region, such as the major histocompatibility complex (MHC), requires extensive population data for both genotypes and phenotypes. The MHC consists of several tightly linked loci with both allelic and gene content variation, making it challenging to genotype. Eight class IIa haplotypes have previously been identified in the Soay sheep (Ovis ariesDQA1
Databáze: Directory of Open Access Journals