Peri- and Postpartum Management of Patients With Factor XI Deficiency
| Autor: | Gloria F. Gerber MD, Kelsey A. Klute MD, John Chapin MD, James Bussel MD, Maria T. DeSancho MD, MSc |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Clinical and Applied Thrombosis/Hemostasis, Vol 25 (2019) |
| Druh dokumentu: | article |
| ISSN: | 1938-2723 10760296 |
| DOI: | 10.1177/1076029619880262 |
| Popis: | Factor XI (FXI) deficiency is an uncommon autosomal disorder with variable bleeding phenotype, making peripartum management challenging. We describe our experience in pregnant women with FXI deficiency and identify strategies to minimize the use of hemostatic agents and increase utilization of neuraxial anesthesia. Electronic records of 28 pregnant women with FXI deficiency seen by a hematology service in an academic medical center from January 2006 to August 2018 were reviewed. Data on bleeding, obstetric history, peripartum management, and FXI activity were collected. Partial FXI deficiency was defined as > 20 IU/dL and severe |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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