Autor: |
Cássio Marques Perlin, Vinicius Lins Ferreira, Helena Hiemisch Lobo Borba, Astrid Wiens, Cláudia Alexandra Pontes Ivantes, Luana Lenzi, Roberto Pontarolo |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
|
Zdroj: |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 59, Iss 0 (2017) |
Druh dokumentu: |
article |
ISSN: |
1678-9946 |
DOI: |
10.1590/s1678-9946201759081 |
Popis: |
ABSTRACT Introduction: Multiple factors negatively affect the quality of life of patients infected with hepatitis C virus. This study aims to evaluate the effect of pharmacological treatment on the quality of life of these individuals. Methods: This is a cross-sectional study conducted in two Southern Brazilian centers that used two instruments (a generic and a specific one) for measuring the quality of life in patients with chronic hepatitis C: the Short Form-36 (SF-36); and the Chronic Liver Disease Questionnaire (CLDQ) for liver disease. We included patients from two centers without any treatment (control group), or receiving medication (peginterferon + ribavirin ± telaprevir or boceprevir, i.e., respectively, dual, and triple therapies). Results: One hundred and forty-seven patients were included. Patients under treatment (n = 86) had a lower score in 7 of the 8 SF-36 domains, with statistical significance (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|