| Autor: |
Cássio Marques Perlin, Vinicius Lins Ferreira, Helena Hiemisch Lobo Borba, Astrid Wiens, Cláudia Alexandra Pontes Ivantes, Luana Lenzi, Roberto Pontarolo |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 59, Iss 0 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1678-9946 |
| DOI: |
10.1590/s1678-9946201759081 |
| Popis: |
ABSTRACT Introduction: Multiple factors negatively affect the quality of life of patients infected with hepatitis C virus. This study aims to evaluate the effect of pharmacological treatment on the quality of life of these individuals. Methods: This is a cross-sectional study conducted in two Southern Brazilian centers that used two instruments (a generic and a specific one) for measuring the quality of life in patients with chronic hepatitis C: the Short Form-36 (SF-36); and the Chronic Liver Disease Questionnaire (CLDQ) for liver disease. We included patients from two centers without any treatment (control group), or receiving medication (peginterferon + ribavirin ± telaprevir or boceprevir, i.e., respectively, dual, and triple therapies). Results: One hundred and forty-seven patients were included. Patients under treatment (n = 86) had a lower score in 7 of the 8 SF-36 domains, with statistical significance (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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