Zingerone ameliorates tellurium induced nephrotoxicity by abating elevated serum markers in the rats
| Autor: | Mohammad Firoz Alam, Saeed Alshahrani, Essam Alamir, Mohammad Abdurrhman Alhazmi, Tarique Anwer, Gyas Khan, Moni Sivakumar Sivagurunathan |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Environment Conservation Journal, Vol 21, Iss 1&2 (2020) |
| Druh dokumentu: | article |
| ISSN: | 0972-3099 2278-5124 |
| DOI: | 10.36953/ECJ.2020.211214 |
| Popis: | The present study was designed to investigate the nephrotoxicity of tellurium (Sodium tellurite) in rats through evaluating the level of kidney functional marker enzymes and its treatment with Zingerone. Rats were divided into four groups, Group-A (control group), Group-B (tellurium treated group), Group-C (tellurium + Zingerone treatment group), and Group-D (Zingerone treatment alone) and each group have six animals. Tellurium was given in Group-B and Group-C at the dose of 8.3mg/kg bodyweight daily orally for 15 days, while Zingerone of 100mg/kg body weight was given in Group-C as pre- and post-treatment orally for 15days. Group-D was given alone Zingerone of 100mg/kg bodyweight; orally for 15 days. Results revealed that tellurium administration significantly (P |
| Databáze: | Directory of Open Access Journals |
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