Levels of Nitric Oxide in Gastric Juice of Smoker and Non-smoker

Autor: M Rahbani-Nobar, MH Somi, A Fattahi, N Dolatkhah, M Nourazarian, S J Seyedi-Khoshknab, B Pourasghari, H Dolatkhah
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Medical Laboratory Journal, Vol 4, Iss 2, Pp 17-25 (2010)
Druh dokumentu: article
ISSN: 2538-4449
Popis: Abstract Bachground and objectives: Epidemiological studies have shown that using tobacco products is one of the main factors in forming malignancies in various tissues of the body. There is more than 600 μgr nitric oxide radical (NO°) in gas phase in each cigarette with fresh smoke. Hence, oxidation of nitrogen components in tobacco, more than 100 μgr of atmospheric NO°is produced by smoking, would be transferred to the body without any filtration. We studied nitric oxide levels in the gastric juice of smokers and non-smokers patients with active peptic ulcer. Material and Methods: In this study, 43 smoker patients with active peptic ulcer (14 female & 29 male) referred to gastroenterology clinic with mean age of 45.30±13.16 as case group.Forthy-three non-smokers without peptic ulcer (13 female & 30 male) aged 42.67±16.04, 43 smoker without peptic ulcer (16 female & 27 male) with mean age of 44.58±12.07 and 43 non-smoker with active peptic ulcer (20 female & 23 male) with mean age of 45.37±13.39 were selected as control groups of 1, 2 and 3 ,respectively. The level of Nitric oxide in gastric juice was measured by using Greiss colorimetric method. Results: Comparing with control group one and two, meaningful rise is noticed in mean level of nitric oxide case group (p
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