Textural Analysis of the Hyperdense Artery Sign in Patients with Acute Ischemic Stroke Predicts the Outcome of Thrombectomy

Autor: Lucian Mărginean, Rares Cristian Filep, Bogdan Andrei Suciu, Tudor G. Jovin, Paul-Andrei Ștefan, Roxana-Adelina Lupean, Eliza Mihaela Arbănași, Emil Marian Arbănași, Diana Roxana Opriș, Alexander Niklas Timm, Rareș Vodă, Vlad Vunvulea
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Cardiovascular Development and Disease, Vol 10, Iss 9, p 359 (2023)
Druh dokumentu: article
ISSN: 2308-3425
DOI: 10.3390/jcdd10090359
Popis: Textural analysis is pivotal in augmenting the diagnosis and outcomes of endovascular procedures for stroke patients. Due to the detection of changes imperceptible to the human eye, this type of analysis can potentially aid in deciding the optimal type of endovascular treatment. We included 40 patients who suffered from acute ischemic stroke caused by large vessel occlusion, and calculated 130 different textural features based on the non-enhanced CT scan using an open-source software (3D Slicer). Using chi-squared and Mann–Whitney tests and receiver operating characteristics analysis, we identified a total of 21 different textural parameters capable of predicting the outcome of thrombectomy (quantified as the mTICI score), with variable sensitivity (50–97.9%) and specificity (64.6–99.4%) rates. In conclusion, CT-based radiomics features are potential factors that can predict the outcome of thrombectomy in patients suffering from acute ischemic stroke, aiding in the decision between aspiration, mechanical, or combined thrombectomy procedure.
Databáze: Directory of Open Access Journals