Sex matters in the association between cardiovascular health and incident dementia: evidence from real world data

Autor:	Anna Ponjoan, Jordi Blanch, Ester Fages-Masmiquel, Ruth Martí-Lluch, Lia Alves-Cabratosa, María del Mar Garcia-Gil, Gina Domínguez-Armengol, Francesc Ribas-Aulinas, Lluís Zacarías-Pons, Rafel Ramos
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Electronic health records General practitioner Primary health care Family practice Heart disease risk factors Diabetes Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Zdroj:	Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-10 (2024)
Druh dokumentu:	article
ISSN:	1758-9193
DOI:	10.1186/s13195-024-01406-x
Popis:	Abstract Background Cardiovascular health has been associated with dementia onset, but little is known about the variation of such association by sex and age considering dementia subtypes. We assessed the role of sex and age in the association between cardiovascular risk and the onset of all-cause dementia, Alzheimer’s disease, and vascular dementia in people aged 50–74 years. Methods This is a retrospective cohort study covering 922.973 Catalans who attended the primary care services of the Catalan Health Institute (Spain). Data were obtained from the System for the Development of Research in Primary Care (SIDIAP database). Exposure was the cardiovascular risk (CVR) at baseline categorized into four levels of Framingham-REGICOR score (FRS): low (FRS
Databáze:	Directory of Open Access Journals
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