Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair

Autor: N. Pien, Y. Van de Maele, L. Parmentier, M. Meeremans, A. Mignon, C. De Schauwer, I. Peeters, L. De Wilde, A. Martens, D. Mantovani, S. Van Vlierberghe, P. Dubruel
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Materials Science: Materials in Medicine, Vol 33, Iss 6, Pp 1-17 (2022)
Druh dokumentu: article
ISSN: 1573-4838
DOI: 10.1007/s10856-022-06673-4
Popis: Highlights Synthesis of a novel acrylate-endcapped urethane-based precursor (AUP). Physico-chemical characterization of the developed AUP material. Development of a reinforced electrospun tubular repair construct containing bioactive components. Mechanical evaluation of the repair constructs on ex vivo sheep tendons. Biological evaluation of the repair constructs by means of indirect and direct testing using mono- and co-cultures.
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