Assessment of macular function in patients with non-vascularized pigment epithelial detachment

Autor: Marie Kitano, Asahi Fujita, Ryo Asaoka, Tatsuya Inoue, Tatsuaki Amari, Kayoko Komatsu, Motoshi Yamamoto, Asako Ogawa, Nobuyori Aoki, Masahiro Yamanari, Satoshi Sugiyama, Makoto Aihara, Satoshi Kato, Keiko Azuma, Maiko Maruyama-Inoue, Kazuaki Kadonosono, Ryo Obata
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-021-96151-8
Popis: Abstract Non-vascularized pigment epithelial detachments (PED) are usually associated with dry age-related macular degeneration (AMD). In this study, we aimed to investigate the correlation between visual function and morphologic parameters. Seventeen eyes of eleven patients with non-vascularized AMD were enrolled. In addition to conventional optical coherence tomography (OCT), polarization-sensitive optical coherence tomography (PS-OCT) measurements were performed by evaluating the regularity of retinal pigment epithelium (RPE) entropy within the PED area. Retinal sensitivity was measured with MP-3 microperimetry, and retinal sensitivities within (RSin) and outside (RSout) the PED area were calculated. The relationship between OCT parameters and visual function was analyzed. As a result, there was a significant difference between the RSin and RSout (p
Databáze: Directory of Open Access Journals
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