Association between cognitive dysfunction and diabetes in patients over 65 years old: a cross-sectional study using propensity score matching

Autor: Liwen Zhai, Yao Yang, Jun Zhang, Weiqian Hou, Yujie Yang, Dongfang Ding, Conghui Li, Yi Zhu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Rehabilitation Medicine, Vol 56 (2024)
Druh dokumentu: article
ISSN: 1651-2081
DOI: 10.2340/jrm.v56.18372
Popis: Objectives: To investigate the association between diabetes and cognitive dysfunction in the elderly population, and examine the impact of cognitive dysfunction on level of activities of daily living (ADL) in patients with diabetes. Methods: Data analysis was conducted on 2,951 individuals aged over 65 years from the Chinese Longitudinal Healthy Longevity Survey cohort. Propensity score matching was utilized to mitigate selection bias. Multivariate binary logistic regression was performed to analyse the association between diabetes and cognitive dysfunction in the study subjects. In addition, the relationship between ADL and cognitive function in patients with diabetes was analysed using the Wilcoxon rank-sum test. Results: A significant association (p = 0.017) was found between diabetes and the occurrence of cognitive dysfunction in older adults. Subgroup analyses revealed that diabetes patients with cognitive dysfunction exhibited a worse ADL dependence compared with those without cognitive dysfunction (p
Databáze: Directory of Open Access Journals