Autor: |
Jianmei Zhao, Qingmei Liu, Caifeng Zhang, Kuanshou Zhang, Pengfei Xin |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
BMC Oral Health, Vol 24, Iss 1, Pp 1-12 (2024) |
Druh dokumentu: |
article |
ISSN: |
1472-6831 |
DOI: |
10.1186/s12903-024-04943-x |
Popis: |
Abstract Background Shortening retention time and minimizing relapse rates are ongoing challenges in orthodontics. This study investigated the effects of natural fulvic acids (FAs) and low-level laser therapy (LLLT) on orthodontic retention in rats. Methods Seventy-two male Sprague-Dawley rats underwent mesial movement of the left maxillary first molar using a 50 g force via a nickel-titanium tension spring. After three weeks of movement, the rats entered the retention phase with retainer wires and were divided into four groups: Control (no intervention), FAs (80 mg/kg orally daily), LLLT (808 nm laser twice weekly), and FAs + LLLT (both treatments). Retainers were removed on days 7, 14, and 21 for a 3-day relapse assessment. Maxillary impressions were analyzed for relapse rates using 3Shape software, alongside histological and immunohistochemical evaluations of bone morphogenetic protein-2 (BMP-2) expression in periodontal tissues, with differences among groups analyzed using an ordinary two-way analysis of variance (ANOVA). Results The relapse rate decreased over time, particularly at 10, 17, and 24 days (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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