| Autor: |
Rodrigo Lopes da Silva, Zulmira da Silva Batista, Gerusinete Rodrigues Bastos, Ana Paula Almeida Cunha, Fábio Vidal Figueiredo, Lailson Oliveira de Castro, Liwerbeth dos Anjos Pereira, Marcos Antonio Custódio Neto da Silva, Flávia Castello Branco Vidal, Maria Claudene Barros, Elmary da Costa Fraga, Luciane Maria Oliveira Brito, Maria do Carmo Lacerda Barbosa, Miguel Ângelo Martins Moreira, Maria do Desterro Soares Brandão Nascimento |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
BMC Women's Health, Vol 20, Iss 1, Pp 1-11 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1472-6874 |
| DOI: |
10.1186/s12905-020-01035-0 |
| Popis: |
Abstract Background Cervical cancer is the fourth most common type of cancer affecting women globally. In Brazil, it is the third most frequent type of cancer in women and HPV is present in approximately 90% of cases. Evidence suggests that variants of HPV 16 can interfere biologically and etiologically during the development of cervical cancer. Methods Cervix tumor fragments were collected, their DNA was extracted, and nested PCR was used to detect HPV. Positive samples were sequenced to determine the viral genotype. To characterize the HPV 16 strains, positive samples PCR was used to amplify the LCR and E6 regions of the HPV 16 virus. Results Data from 120 patients with cervical cancer were analyzed. Most women were between 41 and 54 years of age, had schooling until primary school, a family income between 1 and 2 times the minimum wage and were married/in a consensual union. There was no statistically significant association between HPV or socio-demographic variables and risk factors for cervical cancer (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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