Silylium-Catalyzed Activation of Donor- Acceptor Strained Rings and Annulation with Indoles
| Autor: | Emma G. L. Robert, Jérôme Waser |
|---|---|
| Jazyk: | German<br />English<br />French |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | CHIMIA, Vol 78, Iss 4 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0009-4293 2673-2424 |
| DOI: | 10.2533/chimia.2024.234 |
| Popis: | Leveraging the unique reactivity profile of donor-acceptor aminocyclopropanes and cyclobutanes allows the preparation of complex nitrogen-substituted molecules. While most reports focus on donor-acceptor strained rings with two geminal carbonyl groups as acceptors, mono carbonyl acceptor systems, despite their synthetic relevance, have been considerably less studied. Herein we describe catalytic annulation reactions ofaminocyclopropane and aminocyclobutane monoesters employing silylium catalysis to activate these less reactive donor-acceptor systems. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|