| Autor: |
Xiangjun Chen, Reza A. Badian, Håvard Hynne, Cecilie Delphin Amdal, Bente Brokstad Herlofson, Øygunn Aass Utheim, Kristine Løken Westgaard, Fredrik Fineide, Janicke Liaaen Jensen, Tor Paaske Utheim |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-021-01844-9 |
| Popis: |
Abstract Patients undergoing intensity-modulated radiotherapy (IMRT) for head and neck cancer may have increased incidence of dry eye disease and the exact mechanism is unclear. The present study aims to assess tear film and meibomian gland (MG) features in patients who received IMRT for head and neck cancer not involving the orbital area. Twenty-seven patients (64.7 ± 9.8 years) and 30 age-matched controls (61.4 ± 11.0 years) underwent a comprehensive dry eye work-up. Compared to the control group, the patients had more lid margin abnormalities, and worse meibum quality. The MG loss, calculated as (tarsal area-MG area)/tarsal area, was higher in the patient group in both the upper (53.0 ± 12.0% vs. 35.1 ± 10.3%, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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