Autor: |
Roberto Yañez-Macías, Alexandra Muñoz-Bonilla, Marco A. De Jesús-Tellez, Hortensia Maldonado-Textle, Carlos Guerrero-Sánchez, Ulrich S. Schubert, Ramiro Guerrero-Santos |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Polymers, Vol 11, Iss 11, p 1789 (2019) |
Druh dokumentu: |
article |
ISSN: |
2073-4360 |
DOI: |
10.3390/polym11111789 |
Popis: |
The rise of antibiotic-resistant microorganisms has become a critical issue in recent years and has promoted substantial research efforts directed to the development of more effective antimicrobial therapies utilizing different bactericidal mechanisms to neutralize infectious diseases. Modern approaches employ at least two mixed bioactive agents to enhance bactericidal effects. However, the combinations of drugs may not always show a synergistic effect, and further, could also produce adverse effects or stimulate negative outcomes. Therefore, investigations providing insights into the effective utilization of combinations of biocidal agents are of great interest. Sometimes, combination therapy is needed to avoid resistance development in difficult-to-treat infections or biofilm-associated infections treated with common biocides. Thus, this contribution reviews the literature reports discussing the usage of antimicrobial polymers along with nanomaterials or other inhibitors for the development of more potent biocidal therapies. |
Databáze: |
Directory of Open Access Journals |
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