Combinations of Antimicrobial Polymers with Nanomaterials and Bioactives to Improve Biocidal Therapies

Autor: Roberto Yañez-Macías, Alexandra Muñoz-Bonilla, Marco A. De Jesús-Tellez, Hortensia Maldonado-Textle, Carlos Guerrero-Sánchez, Ulrich S. Schubert, Ramiro Guerrero-Santos
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Polymers, Vol 11, Iss 11, p 1789 (2019)
Druh dokumentu: article
ISSN: 2073-4360
DOI: 10.3390/polym11111789
Popis: The rise of antibiotic-resistant microorganisms has become a critical issue in recent years and has promoted substantial research efforts directed to the development of more effective antimicrobial therapies utilizing different bactericidal mechanisms to neutralize infectious diseases. Modern approaches employ at least two mixed bioactive agents to enhance bactericidal effects. However, the combinations of drugs may not always show a synergistic effect, and further, could also produce adverse effects or stimulate negative outcomes. Therefore, investigations providing insights into the effective utilization of combinations of biocidal agents are of great interest. Sometimes, combination therapy is needed to avoid resistance development in difficult-to-treat infections or biofilm-associated infections treated with common biocides. Thus, this contribution reviews the literature reports discussing the usage of antimicrobial polymers along with nanomaterials or other inhibitors for the development of more potent biocidal therapies.
Databáze: Directory of Open Access Journals
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