| Autor: |
Shale J. Mack, BS, Hamza Rshaidat, MD, Annie Ho, BS, Brian M. Till, MD, Micaela L. Collins, MD, MPH, Gregory L. Whitehorn, BS, Jonathan Martin, BS, John D. Jacob, MD, Tyler R. Grenda, MD, Nathaniel R. Evans, III, MD, Olugbenga T. Okusanya, MD |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Annals of Thoracic Surgery Short Reports, Vol 2, Iss 3, Pp 453-457 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2772-9931 |
| DOI: |
10.1016/j.atssr.2024.02.008 |
| Popis: |
Background: The real-world safety of robotic resections after neoadjuvant chemoimmunotherapy remains poorly defined in patients with non-small cell lung cancer. Due to reported increased operative challenges after neoadjuvant immunotherapy, we aim to describe our early institutional experience and outcomes after robotic resection in this clinical context. Methods: We performed a retrospective chart review of patients with non-small cell lung cancer who underwent a robotic lobectomy, comparing patients from June 1, 2022, through October 31, 2023, who were treated with neoadjuvant chemoimmunotherapy consistent with the Checkmate-816 protocol and a control group with upfront resection. Results: A total of 21 patients underwent neoadjuvant chemoimmunotherapy and robotic lobectomy in our cohort, and 64 patients were in the control group. Compared with control, the median tumor size was 3.2 cm vs 2.0 cm (P = .001). The most common clinical stage was IIIA (11 patients, 52%) in the neoadjuvant chemoimmunotherapy group and IA2 in the control group (26 patients, 45%) (P < .001). Operative time was greater in the neoadjuvant chemoimmunotherapy group (224 vs 177 minutes, P = .011). The median quantity of lymph nodes resected in the neoadjuvant chemoimmunotherapy group was greater (21 vs 16.5, P = .042). A R0 resection was achieved in all cases and no conversions to an open lobectomy occurred. Postoperative length of stay was 2 days in both groups (P = .92), and there were similar rates of postoperative air leak (33% vs 48%, P = .23) and acute post-hemorrhagic anemia (19% vs 14%, P = .58). Conclusions: In our cohort, robotic-assisted lobectomy was safe and of comparable quality in the setting of neoadjuvant chemoimmunotherapy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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