| Autor: |
Hunkyung Kim, Takao Suzuki, Miji Kim, Narumi Kojima, Noriyasu Ota, Akira Shimotoyodome, Tadashi Hase, Erika Hosoi, Hideyo Yoshida |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 10, Iss 2, p e0116256 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0116256 |
| Popis: |
OBJECTIVE:To investigate the combined and separate effects of exercise and milk fat globule membrane (MFGM) supplementation on frailty, physical function, physical activity level, and hematological parameters in community-dwelling elderly Japanese women. METHODS:A total of 131 frail, elderly women over 75 years were randomly assigned to one of four groups: exercise and MFGM supplementation (Ex+MFGM), exercise and placebo (Ex+Plac), MFGM supplementation, or the placebo group. The exercise group attended a 60-minute training program twice a week for three months, and the MFGM group ingested 1g of the MFGM supplement in pill form, daily for 3 months. The primary outcome measure was change in frailty status based on Fried's frailty phenotype. Secondary outcome measures included body composition, physical function and hematological parameters, and interview survey components assessing lifestyle factors. Participants were followed for 4 months post-intervention. RESULTS:Significant group × time interactions were observed for usual walking speed (P = 0.005), timed up & go (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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