The effect of carbon nanoparticles staining on lymph node tracking in colorectal cancer: A propensity score matching analysis

Autor: Fei Liu, Dong Peng, Xiao-Yu Liu, Xu-Rui Liu, Zi-Wei Li, Zheng-Qiang Wei, Chun-Yi Wang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Surgery, Vol 10 (2023)
Druh dokumentu: article
ISSN: 2296-875X
DOI: 10.3389/fsurg.2023.1113659
Popis: PurposeThe aim of this study was to evaluate the effect of carbon nanoparticles staining (CNS) on colorectal cancer (CRC) surgery, lymph node tracing and postoperative complications using propensity score matching (PSM).MethodPatients who were diagnosed with CRC and underwent surgery were retrospectively collected from a single clinical center from Jan 2011 to Dec 2021. Baseline characteristics, surgical information and postoperative information were compared between the CNS group and the non-CNS group. PSM was used to eliminate bias.ResultsA total of 6,886 patients were enrolled for retrospective analysis. There were 2,078 (30.2%) patients in the CNS group and 4,808 (69.8%) patients in the non-CNS group. After using 1: 1 ratio PSM to eliminate bias, there were 2,045 patients left in each group. Meanwhile, all of their baseline characteristics were well matched and there was no statistical significance between the two groups (P > 0.05). In terms of surgical information and short-term outcomes, the CNS group had less intraoperative blood loss (P 0.05).ConclusionPreoperative CNS could help the surgeons detect more lymph nodes, thus better determining the patient's N stage. Furthermore, it could reduce intraoperative blood loss and reduce the hospital stay.
Databáze: Directory of Open Access Journals