Pleomorphic adenoma with extensive squamous metaplasia: The first well-documented case involving the submandibular gland

Autor: David A. Gaskin, Alain Reid, Pamela S. Gaskin
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Human Pathology Reports, Vol 27, Iss , Pp 300600- (2022)
Druh dokumentu: article
ISSN: 2772-736X
DOI: 10.1016/j.hpr.2022.300600
Popis: Background: Pleomorphic adenoma with extensive squamous metaplasia is relatively uncommon. Most reported cases in the English literature have involved the minor salivary glands. Case report: A 49-year-old male presented with a 5-year history of a right submandibular lump diagnosed as an adenoma on ultrasound. Excision was conducted under general anesthesia. Histological evaluation revealed a pleomorphic adenoma with extensive squamous metaplasia. Discussion: Pleomorphic adenoma with extensive squamous metaplasia can present a diagnostic dilemma as the differential diagnoses include benign and malignant entities, this is particularly so for small biopsy specimens. We describe an unusual occurrence of this entity in a major salivary gland and discuss its differential diagnoses.
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