Antiphospholipid syndrome, ferritin and fever: Hyperferritinemic syndrome a nosological ally
| Autor: | Andrei Blanaru, Mara Adelina Benchea, Doina Nitescu, Iulia Diana Florescu, Razvan Adrian Ionescu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Romanian Journal of Rheumatology, Vol 32, Iss 2, Pp 76-85 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1843-0791 2069-6086 |
| DOI: | 10.37897/RJR.2023.2.6 |
| Popis: | Hyperferritinemic syndrome represents a common nosological classification for systemic inflammatory syndromes, including Catastrophic antiphospholipid syndrome, in which hyperferritinemia (> 500 ng/mL) is present. Recent studies suggest that in this syndrome, ferritin is more than a passive marker of inflammation, playing an active role in the process. We present the case of a 74-year-old female patient with elevated serum ferritin levels (above 1000 ng/mL), along with an intense inflammatory syndrome, non-immune thrombotic microangiopathy, and multisystem involvement (pulmonary, cardiac, hepatic, pancreatic, neurological and renal changes), outlining the picture of a hyperferritinemic syndrome that is hard to classify otherwise. This underlines the necessity for diagnostic and classification criteria for this pathology. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|