| Autor: |
Jewelle Methazia, Emery Ladi Ngamasana, Wells Utembe, Modupe Ogunrombi, Peter Nyasulu |
| Jazyk: |
English<br />French |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
The Pan African Medical Journal, Vol 37, Iss 93 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1937-8688 |
| DOI: |
10.11604/pamj.2020.37.93.22244 |
| Popis: |
INTRODUCTION: Maternal anaemia is a major public health problem in developing countries. Data suggests that anemia contributes to progression of HIV-infection. The aim of this study was to investigate if pregnancy was an aggravating factor for anaemia among HIV-positive women on anti-retroviral treatment (ART). METHODS: we analyzed data of all HIV-positive women aged 18-49 years receiving ART at Themba Lethu Clinic, Helen Joseph Hospital, Johannesburg, South Africa, from 1st April 2004- 30th April 2011. HIV-positive pregnant women were matched with non-pregnant women using the year of initiation of treatment. The outcome of interest ´anaemia´ was defined as "no anaemia", “anaemia" and "moderate/severe anaemia". We fitted an ordered logistic regression model to predict the likelihood of having severe/moderate anaemia versus no anaemia. We included pregnancy status as a predictor of the outcome and controlled the effect of other covariates in the analysis. RESULTS: the study included 236 HIV positive patients, of which half (n=118, 50%) were pregnant. At baseline, about (n=143, 60%) of patients were anemic. The proportion of pregnant women classified as anemic (anaemia, moderate/severe) differed significantly (p=0.02) from that of non-pregnant women. The following characteristics were significantly associated with anaemia at baseline: BMI category (p=0.01); WHO stage (p=0.001) and CD4 count (p=0.001). Seven months after initiation of treatment, the proportion of HIV positive women with anaemia decreased significantly. CONCLUSION: anaemia is a significant risk factor for untoward health outcomes, especially among HIV-positive pregnant women. Early ART access might result in a significant decrease in anaemia in pregnancy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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