| Autor: |
Rupert P. Williams, Kaleab N. Asrress, Matthew Lumley, Satpal Arri, Tiffany Patterson, Howard Ellis, Vasiliki Manou‐Stathopoulou, Catherine Macfarlane, Shruthi Chandran, Kostantinos Moschonas, Pippa Oakeshott, Timothy Lockie, Amedeo Chiribiri, Brian Clapp, Divaka Perera, Sven Plein, Michael S. Marber, Simon R. Redwood |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 14 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2047-9980 |
| DOI: |
10.1161/JAHA.118.008837 |
| Popis: |
Background Cold air inhalation during exercise increases cardiac mortality, but the pathophysiology is unclear. During cold and exercise, dual‐sensor intracoronary wires measured coronary microvascular resistance (MVR) and blood flow velocity (CBF), and cardiac magnetic resonance measured subendocardial perfusion. Methods and Results Forty‐two patients (62±9 years) undergoing cardiac catheterization, 32 with obstructive coronary stenoses and 10 without, performed either (1) 5 minutes of cold air inhalation (5°F) or (2) two 5‐minute supine‐cycling periods: 1 at room temperature and 1 during cold air inhalation (5°F) (randomized order). We compared rest and peak stress MVR, CBF, and subendocardial perfusion measurements. In patients with unobstructed coronary arteries (n=10), cold air inhalation at rest decreased MVR by 6% (P=0.41), increasing CBF by 20% (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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