Thrombotic microangiopathy following a minor gynaecological procedure in the setting of endometrial cancer: a case report

Autor: Lucinda Barry, Helen Manning, Emma Chesterman, Louis Izzo, Sacha Strockyj
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Case Reports in Women's Health, Vol 32, Iss , Pp e00354- (2021)
Druh dokumentu: article
ISSN: 2214-9112
DOI: 10.1016/j.crwh.2021.e00354
Popis: Hysteroscopy dilatation and curettage is a common minor gynaecological procedure utilised for diagnostic or therapeutic purposes. A 62-year-old woman underwent a hysteroscopy, dilatation and curettage for investigation of prolonged post-menopausal bleeding. Unexpected uterine haemorrhage was encountered without evidence of uterine perforation causing haemodynamic instability. A thrombotic microangiopathy was triggered, leading to microangiopathic haemolytic anaemia, thrombocytopaenia and evidence of micro-thrombosis causing stroke and end-organ dysfunction, including acute renal failure. The histopathology confirmed stage 1 endometrioid adenocarcinoma. This is the first case report of a thrombotic microangiopathy leading to microangiopathic haemolytic anaemia in a patient with endometrioid adenocarcinoma FIGO grade 1, stage 1B following a minor gynaecological procedure.
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