| Autor: |
Zhongxiang Ren, Yetong Xu, Tiejun Li, Weizhong Sun, Zhiru Tang, Yongsheng Wang, Kaifeng Zhou, Jigang Li, Qi Ding, Kaiyang Liang, Liuting Wu, Yulong Yin, Zhihong Sun |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Animal Nutrition, Vol 10, Iss , Pp 360-371 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6545 |
| DOI: |
10.1016/j.aninu.2022.06.009 |
| Popis: |
Nicotinamide adenine dinucleotide (NAD+) is an enzyme cofactor, co-substrate, and redox factor in all living cells and is necessary for maintaining cell metabolism. It has been shown that appropriate supplementation of NAD+ precursors or inhibition of NAD+-depleting enzymes can promote mitochondrial oxidative phosphorylation and improve host energy utilization efficiency. In addition, increasing evidence indicates that the gut microbiota plays a pivotal role in host metabolism. Theoretically, there should be a close correlation among NAD+, gut microbiota, and host metabolism; however, the information is limited. In this review, we summarize the metabolic process of NAD+ and its impact on host metabolism, the link between gut microbiota and host metabolism, as well as the potential effects of NAD+ on microbial metabolism, providing a new perspective on the interaction between gut microbiota and host metabolism. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
