Range adaptation in schizophrenia: A one-year longitudinal study

Autor: Ling-ling Wang, Jing-bo Gong, Yi-hang Huang, Shu-hong Shi, Chao Yan, Hui-xin Hu, Yi Wang, Simon S.Y. Lui, Kang Ju, Raymond C.K. Chan
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Schizophrenia Research: Cognition, Vol 35, Iss , Pp 100297- (2024)
Druh dokumentu: article
ISSN: 2215-0013
DOI: 10.1016/j.scog.2023.100297
Popis: Range adaptation refers to the representation of a stimulus value based on its relative position in the range of pre-experienced values. Altered range adaptation in value representation may be related to motivation and pleasure (MAP) deficit in schizophrenia (SCZ). This follow-up study examined the relationship between range adaptation performance and MAP symptoms in SCZ patients. We recruited 26 schizophrenia patients and followed them for 1 year. They completed an experimental task for estimating their range adaptation to outcome value (OV) and expected value (EV) at baseline and after 1 year. At baseline, we found a marginally significant and negative correlation between OV adaptation and avolition symptoms in SCZ patients. Moreover, the 1-year change of EV adaptation was significantly and negatively correlated with the change of self-report pleasure experience. Our results suggest that range adaptation may track the variations of MAP symptoms in SCZ.
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