Pharmacobiological management of hemostasis within clinical backgrounds via Ankaferd hemostat (Ankaferd blood stopper)

Autor: Rafiye Ciftciler, Ali Erdinc Ciftciler, Umit Yavuz Malkan, Ibrahim C Haznedaroglu
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: SAGE Open Medicine, Vol 8 (2020)
Druh dokumentu: article
ISSN: 2050-3121
20503121
DOI: 10.1177/2050312120907811
Popis: Ankaferd hemostat (Ankaferd blood stopper [ABS], Istanbul, Turkey) is a hemostatic agent affecting red blood cell-fibrinogen interactions. ABS has been traditionally used in Anatolia as a hemostatic agent for centuries. ABS contains a standardized combination of the plants namely Glycyrrhiza glabra, Thymus vulgaris, Alpinia officinarum, Vitis vinifera , and Urtica dioica . The hemostatic effect of ABS depends upon the quick promotion of a protein network, particularly fibrinogen gamma, in relation to the erythrocyte aggregation. The aim of this review is to indicate pharmacobiological basis and clinical backgrounds of ABS. Current perspective for using ABS is to provide hemostasis and accelerating wound healing particularly in cases which are difficult to manage. Future controlled trials are needed to elucidate the actions of ABS with in hemostasis, antithrombotic, anti-inflammatory, anti-infective, antifungal, and anti-oxidative effects.
Databáze: Directory of Open Access Journals