Effects of staff education and standardizing dosing and collection times on vancomycin trough appropriateness in ward patients

Autor: Hammond DA, Atkinson LN, James TB, Painter JT, Lusardi K
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Pharmacy Practice, Vol 15, Iss 2, Pp 949-949 (2017)
Druh dokumentu: article
ISSN: 1885-642X
1886-3655
DOI: 10.18549/PharmPract.2017.02.949
Popis: Background: Many institutions have guidelines for initiation and monitoring, but not timing, of vancomycin. Objective: Our objective was to evaluate vancomycin trough collection appropriateness before and after an initiative to change the dosing and trough collection times in ward patients. Methods: A retrospective cohort study of ward patients from May 2014-16 who received scheduled intravenous vancomycin was performed. Nurse managers and pharmacists provided staff education. Differences between pre- and post-intervention groups were compared using student's t-test for continuous data and chi-square test for categorical data. Results: Baseline characteristics were similar between the pre-intervention (n=124) and post-intervention (n=122) groups except for weight-based maintenance dose (15.3 mg/kg vs. 16.5 mg/kg, p=0.03) and percentage of troughs collected with morning labs (14% vs. 87%, p
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