Neutralizing Antibodies against Enteroviruses in Patients with Hand, Foot and Mouth Disease
Autor: | Lam Anh Nguyet, Tran Tan Thanh, Le Nguyen Thanh Nhan, Nguyen Thi Thu Hong, Le Nguyen Truc Nhu, Hoang Minh Tu Van, Nguyen Thi Han Ny, Nguyen To Anh, Do Duong Kim Han, Ha Manh Tuan, Vu Quang Huy, Ho Lu Viet, Hoang Quoc Cuong, Nguyen Thi Thanh Thao, Do Chau Viet, Truong Huu Khanh, Louise Thwaites, Hannah Clapham, Nguyen Thanh Hung, Nguyen Van Vinh Chau, Guy Thwaites, Do Quang Ha, H. Rogier van Doorn, Le Van Tan |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Emerging Infectious Diseases, Vol 26, Iss 2, Pp 298-306 (2020) |
Druh dokumentu: | article |
ISSN: | 1080-6040 1080-6059 |
DOI: | 10.3201/eid2602.190721 |
Popis: | Hand, foot and mouth disease (HFMD) is an emerging infection with pandemic potential. Knowledge of neutralizing antibody responses among its pathogens is essential to inform vaccine development and epidemiologic research. We used 120 paired-plasma samples collected at enrollment and >7 days after the onset of illness from HFMD patients infected with enterovirus A71 (EV-A71), coxsackievirus A (CVA) 6, CVA10, and CVA16 to study cross neutralization. For homotypic viruses, seropositivity increased from |
Databáze: | Directory of Open Access Journals |
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