RESEARCH OF THE POLYMORPHIC VARIANTS OF TGFβ CONTRIBUTION IN FORMATION OF CHROMOSOMAL DAMAGE OF KUZBASS MINERS

Autor: Anastasiya Olegovna Sokolova, Varvara Ivanovna Minina
Jazyk: English<br />Russian
Rok vydání: 2019
Předmět:
Zdroj: Siberian Journal of Life Sciences and Agriculture, Vol 11, Iss 5-2, Pp 129-133 (2019)
Druh dokumentu: article
ISSN: 2658-6649
2658-6657
DOI: 10.12731/2658-6649-2019-11-5-2-129-133
Popis: The effect of polymorphic variant of TGFβ gene on chromosome damage of Kuzbass miners was studied. The frequency of chromosomal aberrations among miners was increased (compared with the control group, p=0,000001). We discovered that TGFβ gene polymorphism increases the frequency of chromosomal damage (chromatide exchanges, single fragments) among miners.
Databáze: Directory of Open Access Journals