Social determinants of health associated with COVID-19 severity during pregnancy: a multinational cohort study (in the International Registry of Coronavirus Exposure in Pregnancy)

Autor: Jasmine A Mack, Erica A Voss, Rada Rusu, Meg Celine Hernandez, Sonia Hernandez-Diaz, Diego F Wyszynski, Shirley Sylvester, Rachael L DiSantostefano
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Public Health, Vol 22, Iss 1, Pp 1-12 (2022)
Druh dokumentu: article
ISSN: 1471-2458
DOI: 10.1186/s12889-022-14532-8
Popis: Abstract Background The COVID-19 pandemic has caused morbidity and mortality, particularly among vulnerable populations. We aimed to assess social and demographic characteristics associated with COVID-19 severity among symptomatic participants during pregnancy. Methods The International Registry of Coronavirus Exposure in Pregnancy is a multinational, longitudinal observational cohort study of adult participants tested for SARS-CoV-2 or who received clinical diagnosis of COVID-19 during pregnancy (NCT04366986). Disease severity status of mild, moderate, or severe was determined based on symptoms and healthcare utilization. Stratified by current versus recent pregnancy at enrollment, univariate mixed-effects logistic regression modeling was used to characterize association between social and demographic characteristics with COVID-19 severity, using a cumulative mixed effect model with country as a random effect. Results The odds of developing more severe COVID-19 (odds ratio [95% confidence interval]) were higher among participants with lower socioeconomic status (poor: 2.72 [2.01,3.69]; lower-middle class: 2.07 [1.62,2.65] vs wealthy), among participants with lower educational attainment (high school: 1.68 [1.39,2.03];
Databáze: Directory of Open Access Journals
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