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The Internet of Medical Things (IoMT) links medical devices and wearable, enhancing healthcare. To secure sensitive patient data over the IoMT, encryption is vital to retain confidentiality, prevent tampering, ensure authenticity, and secure data transfer. The intricate neural network architecture of deep learning models adds a layer of complexity and non-linearity to the encryption process, rendering it highly resistant to plaintext attacks. Specifically, the Cycle_GAN network is used as the leading learning network. This work suggests deep learning-based encryption for medical images using Cycle_GAN, a Generative Adversarial Network. Cycle_GAN changes images without paired training data that improves quality and feature preservation. Unlike conventional image-to-image translation techniques, Cycle_GAN doesn’t require a dataset with corresponding input–output pairs. Traditional methods typically needs paired data to learn the mapping between input and output images. Paired data can be challenging to obtain, specifically in medical imaging where gathering and annotating data can be time-consuming, laborious and expensive. The use of Cycle_GAN overwhelms this constraint by using unpaired data, where the input and output images are not explicitly paired. This method ensures confidentiality, authenticity, and secure transfer. Cycle_GAN consists of two major components: a generator used to modify the images, and a discriminator used to distinguish between real and fake images. Further, the Binary-Cross Entropy loss function is employed to train the network for precise predictions. The experiments are carried out on skin cancer datasets. The results demonstrate high-level efficient, systematic and coherent encryption as compared with other modernized medical image encryption methods. The proposed technique offers several benefits, including efficient encryption and decryption and robustness against unauthorized access. |