Molecular mechanism of azoxy bond formation for azoxymycins biosynthesis

Autor: Yuan-Yang Guo, Zhen-Hua Li, Tian-Yu Xia, Yi-Ling Du, Xu-Ming Mao, Yong-Quan Li
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-12250-1
Popis: Azoxy bonds are frequently found in liquid crystals, chemical intermediates, dyes, agrochemicals and pharmaceuticals. Here, the authors investigated azoxy bond formation by the non-heme diiron N-oxygenase AzoC in azoxymycin biosynthesis and show that the nitroso group plays a key part in it.
Databáze: Directory of Open Access Journals