Egg white hydrolysate from simulated gastrointestinal digestion alleviates the inflammation and improves the nutritional status in TNBS-induced Crohn’s disease rats

Autor: Tianliang Wu, Juanrui Li, Wei Wang, Chenxi Xu, Liying Wang, Long Ding
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Functional Foods, Vol 98, Iss , Pp 105288- (2022)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2022.105288
Popis: This paper aimed to investigate the amelioration of egg white hydrolysate (EWH) in Crohn’s disease. Male Sprague-Dawley rats were rectally administrated tri­nitrobenzene sulfonic acid (TNBS) (100 mg/kg) at day 0 to induce CD and then intragastrically administrated saline (model group, n = 8) or EWH (1 g/kg) (EWH group, n = 8) for four weeks. Results showed that the EWH group had higher food intake, lower body weight loss, and colonic histopathological damage compared with the model group (P
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