Promising improvement in infected Wound Healing in Type two Diabetic rats by Combined effects of conditioned medium of human adipose-derived stem cells plus Photobiomodulation

Autor:	Kaysan Sohrabi, Houssein Ahmadi, Abdollah Amini, Behnaz Ahrabi, Atarodalsadat Mostafavinia, Hamidreza Omidi, Mansooreh Mirzaei, Fatemeh Fadaei Fathabady, Mohammadjavad Fridoni, Maryam Rahmannia, Sufan Chien, Mohammad Bayat
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Diabetes mellitus Diabetic foot ulcers Human adipose-derived stem cell Conditioned medium Photobiomodulation Microbial flora Medicine (General) R5-920 Biology (General) QH301-705.5
Zdroj:	Laboratory Animal Research, Vol 39, Iss 1, Pp 1-15 (2023)
Druh dokumentu:	article
ISSN:	2233-7660
DOI:	10.1186/s42826-023-00178-z
Popis:	Abstract Background We aimed to examine the accompanying and solo impacts of conditioned medium of human adipose-derived stem cells (h-ASC-COM) and photobiomodulation (PBM) on the maturation stage of an ischemic infected delayed-healing wound model (IIDHWM) of rats with type 2 diabetes (TIIDM). Results Outcomes of the wound closure ratio (WCR) results, tensiometrical microbiological, and stereological assessment followed almost identical patterns. While the outcomes of h-ASC-COM + PBM, PBM only, and h-ASC-COM only regimes were significantly better for all evaluated methods than those of group 1(all, p
Databáze:	Directory of Open Access Journals
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