| Autor: |
Timothy Christie, Bashir Jiwani, Getnet Asrat, Valentina Montessori, Richard Mathias, Julio Montaner |
| Jazyk: |
angličtina |
| Rok vydání: |
2006 |
| Předmět: |
|
| Zdroj: |
Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 17, Iss 1, Pp 15-18 (2006) |
| Druh dokumentu: |
article |
| ISSN: |
1712-9532 |
| DOI: |
10.1155/2006/286301 |
| Popis: |
End-stage liver disease is emerging as a leading cause of death among HIV-positive patients. Historically, an HIV diagnosis was a contraindication for a liver transplant; however, because of the efficacy of highly active antiretroviral therapy (HAART), HIV-positive patients have one-year, two-year, and three-year post-transplantation survival rates similar to that of HIV-negative patients. Based on this evidence, HIV-positive patients are now considered eligible for transplantation. However, newly emerging guidelines include the stipulation that HIV-positive patients must be on HAART to be placed on a waiting list for transplantation. The purpose of the present paper is to evaluate the scientific and ethical probity of requiring HIV-positive patients to be on HAART as a condition for being on a liver transplant waiting list. It is argued that the emphasis should be placed on the probability of post-transplantation HAART tolerance, and that concerns about pretransplantation HAART tolerance are of secondary importance. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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