Study of Surrogate Immunohistochemical Markers IDH1, ATRX, BRAF V600E, and p53 Mutation in Astrocytic and Oligodendroglial Tumors

Autor: Santosh Sharma, Kusum Mathur, Alka Mittal, Meel Mukta, Arpita Jindal, Mukesh Kumar
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Indian Journal of Neurosurgery, Vol 12, Iss 02, Pp 137-146 (2023)
Druh dokumentu: article
ISSN: 2277-954X
2277-9167
DOI: 10.1055/s-0042-1743265
Popis: Introduction In consonance with current the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (2016), histological diagnosis of gliomas should be reinforced by molecular information. This study was performed to determine the frequency of isocitrate dehydrogenase 1 (IDH1), α thalassemia/intellectual disability syndrome X-linked (ATRX), p53, and BRAF V600E mutations in different grade astrocytomas and oligodendrogliomas.
Databáze: Directory of Open Access Journals
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