| Autor: |
B. Subhani, S. Maathury, U. Dissanayake |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Asian Journal of Internal Medicine, Vol 3, Iss 1 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2827-7260 |
| DOI: |
10.4038/ajim.v3i1.121 |
| Popis: |
Sjögren syndrome is a systemic autoimmune disease that primarily affects the exocrine glands. A 36-year-old woman presented with sudden onset of bilateral lower limb weakness. She was noted to have hypokalaemia with a normal anion gap metabolic acidosis. Subsequent investigations revealed high ESR, positive ANA, absent dsDNA, normal C3, C4, positive anti-Ro and negative anti-La. Labial biopsy revealed a lymphocytic infiltrate and renal biopsy revealed tubulointerstitial nephritis. Sjogren’s syndrome rarely (less than 5%) presents for the first time as renal manifestations such as hypokalaemia related paralysis as a result of type I – distal renal tubular acidosis due to the underlying tubulointerstitial nephritis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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