APELLA: Open-Source, miniaturized All-in-One powered Lab-on-a-Disc platform

Autor: Laura Serioli, Atsushi Ishimoto, Akinobu Yamaguchi, Kinga Zór, Anja Boisen, En-Te Hwu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: HardwareX, Vol 15, Iss , Pp e00449- (2023)
Druh dokumentu: article
ISSN: 2468-0672
DOI: 10.1016/j.ohx.2023.e00449
Popis: We present an unconventional approach to a common Lab-on-a-Disc (LoD) that combines a quadcopter propulsion system, a miniaturized 2.4 GHz Wi-Fi spy camera, 9.74 Watt Qi wireless power, and an Arduino into an open-source, miniaturized All-in-one powered lab-on-disc platform (APELLA). The quadcopter propulsion generates thrust to rotate (from 0.1 to 24.5 Hz) or shake the LoD device, while the spy camera enables a real-time (30 frames per second) and high definition (1280 × 720 pixels) visualization of microfluidic channels without requiring a bulky and heavy stroboscopic imaging setup. A mobile device can communicate with an Arduino microcontroller inside the APELLA through a Bluetooth interface for closed loop and sequential frequency control. In a proof-of-concept study, the APELLA achieved comparable mixing efficiency to a traditional spin stand and can capture rapid microfluidic events at low rotational frequencies (
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