The Relationship Between the Mean Platelet Volume and the Development of Spontaneous Ascites Fluid Infection in Patients with Decompensated Cirrhosis

Autor: Ebru Sinem Bilgin, Banu Boyuk, Osman Maviş, Rahime Özgür
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Southern Clinics of Istanbul Eurasia, Vol 31, Iss 3, Pp 219-225 (2020)
Druh dokumentu: article
ISSN: 2587-0998
DOI: 10.14744/scie.2020.09226
Popis: INTRODUCTION[|]Spontaneous ascitic fluid infection (SAI) is one of the frequent and important complication of decompensated cirrhosis with high mortality. Mean platelet volume (MPV) is a parameter that shows the activity, stimulation and production of platelets. Changes in MPV are important indicators of platelet production, and are also an indicator of the severity of many diseases, such as sepsis, thrombosis, or even respiratory distress syndrome. In our study, we aimed to analyze the relationship between spontaneous ascites infection and mean platelet volume. [¤]METHODS[|]98 cirrhosis patients (42 females, 56 males) with various etiologies were participated to the study. The patients were divided into two groups as SAI positive group including patients with ascitic culture positive and/or ascites polymorphonuclear leukocyte count (PMNL) >250 mm3 and SAI negative group including patients with no bacterial reproduction in their ascites fluid culture and ascites PMNL count 0.05). [¤]DISCUSSION AND CONCLUSION[|]Mean platelet volume in patients with spontaneous ascites infection who have developed, decompensated cirrhosis significantly increases. It is possible to use this test which is cheap, non-invasive and fast in the early diagnosis and treatment to follow-up of spontaneous ascites infection.[¤]
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