Management of Hyperlipidemia in Very High and Extreme Risk Patients in Croatia: an Observational Study of Treatment Patterns and Lipid Control

Autor: Hrvoje Pintarić, Marijana Knezović Florijan, Ian Bridges, Robert Steiner, Luka Zaputović, Davor Miličić
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Acta Clinica Croatica, Vol 59., Iss 4., Pp 641-648 (2020)
Druh dokumentu: article
ISSN: 0353-9466
1333-9451
DOI: 10.20471/acc.2020.59.04.10
Popis: Our observational study evaluated current management of elevated low-density lipoprotein cholesterol (LDL -C) in adult secondary prevention patients (all very high risk (VHR) by European guidelines) attending specialist clinics across Croatia. Data were collected retrospectively from patient records for the preceding 12 months. The subset judged to be at extreme risk (ER ; American Association of Clinical Endocrinologists (AACE) criteria; n=48) were compared with the remaining patients (VHR group; n=41). All patients were receiving statins (75.6% VHR/81.3% ER at high-intensity), with only a minority receiving concomitant lipid-lowering treatment (7.3% VHR/16.7% ER ). Median (Q1, Q3) LDL -C levels at the last visit were 1.9 (1.6, 2.4) mmol/L for VHR and 2.1 (1.5, 3.1) mmol/L for ER , with only 41.5% (95% CI 26.3-57.9) of VHR patients and 27.1% (15.3-41.9) of ER patients attaining their LDL -C targets (
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