Approaches to managing patients with CIN in routine clinical practice

Autor: V. G. Anufrieva, E. Yu. Lebedenko, U. M. Magomedova, A. F. Mikhelson
Jazyk: English<br />Russian
Rok vydání: 2020
Předmět:
Zdroj: Медицинский вестник Юга России, Vol 11, Iss 4, Pp 92-98 (2020)
Druh dokumentu: article
ISSN: 2219-8075
2618-7876
DOI: 10.21886/2219-8075-2020-11-4-92-98
Popis: Objective: analyze the validity of destructive treatments for cervical diseases in clinical practice.Materials and methods: analyzed archival medical documentation (medical records of an inpatient patient, form 003/y) of 258 patients who underwent surgical treatment of cervical diseases in 2017 – 2018. Statistical data were calculated on a personal computer using the Microsoft Excel 2011 for Mac program and the «Statistica» statistical program.Results: an analysis of medical documentation revealed that a complete set of diagnostic methods, regulated by the clinical recommendations “Benign and precancerous cervical diseases from the perspective of cancer prevention” (2017), including HPV genotyping, was carried out in 28.7 % women. Before surgical treatment, a cytological examination of the cervix was carried out in 89.5 % cases, HPV-test — 31.4 % patients. As a result of the comparison of 258 histological and pre-operative clinical diagnoses, overdiagnosis of low- and high-grade cervical lesions (LSIL and HSIL) was noted in 16 (23.2 %) patients who did not have a history of childbirth and 42 (22.0 %) women who had previously given birth, which determined the use of destructive treatments without indications in 58 (22.5%) cases. An underestimation of the severity of cervical damage among unborn patients was found in 9 (13.0 %) patients, as well as in 40 (21.2 %) women with a history of childbirth.Conclusions: overdiagnosis of the degree of intraepithelial cervical lesions entails the unreasonable use of destructive methods of treatment in young unborn women who violate the anatomic-functional integrity of the cervix and the architectonics of the cervical canal.
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