OBSTRUCTIVE SLEEP APNEA SYNDROME IN CHILDREN WITH TYPE II MUCOPOLYSACCHARIDOSIS (HUNTER SYNDROME)
| Autor: | N. D. Vashakmadze, L. S. Namazova-Baranova, A. K. Gevorkyan, V. V. Altunin, L. M. Kuzenkova, E. G. Chernavina, M. A. Babaykina, T. V. Podkletnova, O. V. Kozhevnikova |
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| Jazyk: | ruština |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Педиатрическая фармакология, Vol 10, Iss 6, Pp 76-81 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1727-5776 2500-3089 |
| DOI: | 10.15690/pf.v10i6.900 |
| Popis: | 17 children received cardiorespiratory monitoring in order to evaluate spread and dynamics of changes in the primary obstructive sleep apnea syndrome (OSAS) parameters at type II mucopolysaccharidosis. Mild OSAS [apnea/hypopnea index (AHI) – 1.5-5] was diagnosed in 4 patients (23.5%), moderate OSAS (AHI – 5-10) – in 4 patients (23.5%), severe OSAS (AHI>10) – in 2 patients (11.8%). Average AHI at Hunter syndrome was 5.3±6.9/hour. Mild OSAS (AHI – 0.8±0.3/hour) was prevalent in the group of younger children (1-3 years of age); severe OSAS was prevalent in the group of adolescents (AHI – 10.9±9.4/hour); average blood oxygen saturation (SpO2) was 87.5±10.6%, desaturation index – 10.4±13.3/hour. In total, OSAS was observed in 58.8% of children and aggravated in direct proportion to aggravation of the disease course. Thus, cardiorespiratory monitoring is necessary to reveal children with moderate and severe OSAS course with subsequent prevention of life-threatening conditions, which may appear at this syndrome. |
| Databáze: | Directory of Open Access Journals |
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