Rubella virus vaccine-induced granulomas: a case in children with ataxia-telangiectasia

Autor:	Florine Le Lay, Marianna Deparis, Sylvie Fraitag, Anne Dompmartin
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Ataxia telangiectasia immunodeficiency rubella granuloma vaccine Dermatology RL1-803
Zdroj:	Dermatology Reports (2024)
Druh dokumentu:	article
ISSN:	2036-7392 2036-7406
DOI:	10.4081/dr.2024.9864
Popis:	Ataxia telangiectasia (AT) is a rare autosomal recessive primary immunodeficiency disorder (PID) resulting from a mutation in the ATM gene, which is involved in DNA repair. We describe the case of a young girl with cutaneous granulomas that developed after childhood vaccinations. Immunohistochemistry revealed granulomas induced by the rubella virus vaccine. This finding raises the question of live rubella vaccine strains safety in immunocompromised children.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/2205aeb66a374376be5979a9d95f4482 Zobrazit plný text záznamu View record in DOAJ