Oxidative Stress Biomarkers in Urine of Patients with Hepatitis B and C

Autor: Ömer Faruk Kökoğlu, Hasan Uçmak, Ergül Belge Kurutaş, Nurettin Kuzhan, Remzi Toprak, Ali Çetinkaya, Bülent Kantarçeken, Filiz Atalay
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Balkan Medical Journal, Vol 29, Iss 1, Pp 39-42 (2012)
Druh dokumentu: article
ISSN: 2146-3123
2146-3131
Popis: Objective: The aim of our study is to determine the role of oxidative stress biomarkers in hepatic damage in hepatitis B virus (HBV) and hepatitis C virus (HCV)-infected patients. Materials and Methods: Forty-eight patients with chronic hepatitis B, 15 patients with chronic hepatitis C and 30 healthy individuals as a control group were included in this study. Serum alanine-aminotransferase (ALT) and aspartate aminotransferase (AST) levels, urine oxidative stress biomarkers such as malondialdehyde (MDA) levels, superoxide dismutase (SOD-1) and catalase (CAT) activities were measured. Results: Urine MDA levels increased in patients with HBV and HCV compared to the control group. It was higher in HCV patients than HBV patients (p
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