HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
| Autor: | Bernadette Catalan Soares, Anna Bárbara de F Carneiro Proietti, Fernando Augusto Proietti |
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| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Revista de Saúde Pública, Vol 37, Iss 4, Pp 470-476 (2003) |
| Druh dokumentu: | article |
| ISSN: | 1518-8787 0034-8910 |
| DOI: | 10.1590/s0034-89102003000400012 |
| Popis: | OBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity. METHODS: HTLV-I/II seropositive (n=135), indeterminate (n=167) and seronegative blood donors (n=116) were enrolled in an open prevalence prospective cohort study. A cross-sectional epidemiological study of positive, indeterminate and seronegative HTLV-I/II subjects was conducted to assess behavioral and environmental risk factors for seropositivity. HTLV-I/II serological status was confirmed using enzyme-linked immunosorbent assay (EIA) and Western blot (WB). RESULTS: The three groups were not homogeneous. HTLV-I/II seropositivity was associated to past blood transfusion and years of schooling, a marker of socioeconomic status, and use of non-intravenous illegal drugs. CONCLUSIONS: The study results reinforce the importance of continuous monitoring and improvement of blood donor selection process. |
| Databáze: | Directory of Open Access Journals |
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