An overview of animal tissue decellularization techniques and clinical applications

Autor: Catalina Pineda-Molina, Sara María Galvis-Escobar, Juan David Molina-Sierra, Juan Pablo Ruíz-Soto, Maria Antonia Rego-Londoño
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2024
Předmět:
Zdroj: Revista Politécnica, Vol 20, Iss 39, Pp 31-47 (2024)
Druh dokumentu: article
ISSN: 1900-2351
2256-5353
DOI: 10.33571/rpolitec.v20n39a3
Popis: There is a persistent an urgent need to solve tissue and organ donor shortage issues. Decellularized tissues represent a promising alternative to other biologic and synthetic treatments that have been developed, since they aim to retain native tissue characteristics that would help in the regenerative processes such as prolifera-tion, cellular adhesion, and the presence of growth factors, while minimizing the chances of an unwanted host immune response. In the present review, we describe the most common methodologies for decellularization pro-cesses, as well as the clinical applications of these biomaterials.
Databáze: Directory of Open Access Journals