Clinical and anamnestic predictors of postoperative hypoxic and ischemic brain lesions and algorithms for their assessment of neurological support of сardiac surgery patients

Autor: Dmytro S. Mankovskyi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Вісник медичних і біологічних досліджень, Vol 3, Iss 3, Pp 42-48 (2021)
Druh dokumentu: article
ISSN: 2706-6290
2706-6282
DOI: 10.11603/bmbr.2706-6290.2021.3.12568
Popis: Modern technologies of cardiac surgery (CS) can significantly affect the structure of mortality, disability and quality of life of patients with critical ischemic disease, valvular heart disease, cardiomyopathies. In recent years, the overall mortality after CS with the use of artificial circulation (AC) is characterized by a decrease of 20–25 %, while the frequency of hypoxic-ischemic lesions (HIL) of the brain is almost unchanged and, even in older age groups increases. The aim of the study – to develop an algorithm for assessing the risk of hypoxic-ischemic brain lesions as components of neurological support of cardiac surgery patients. Materials and Methods. The study was performed on the clinical basis of the State Institution "Heart Institute of the Ministry of Health of Ukraine" with the use of primary materials on cardiac surgery using artificial circulation; involved two groups of patients, formed by the method of copy-pair (by characteristics: age, sex, type of intervention): in the first (n = 340 people) – patients with brain HIL after interventions, in the second (n = 340 people) – without brain HIL. The study used the results of routine neurological, instrumental and laboratory examinations at the stages of surgical treatment with the completion of a special "Card of expert assessment of neurological support of a patient with cardiac surgery." Results. The comparative intergroup analysis revealed reliable (p
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