Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction
| Autor: | Luna Azulay-Abulafia, Maria Auxiliadora Jeunon Sousa, Andrea Pussanti, Daniel Dal'Asta Coimbra, Hernando Vega, Fred Bernardes Filho |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 4, Pp 533-536 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1678-9849 0037-8682 |
| DOI: | 10.1590/0037-8682-0086-2014 |
| Popis: | Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome. |
| Databáze: | Directory of Open Access Journals |
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